Low-level laser therapy in chemo- and radiation-induced mucositis: results of multicenter phase III studies

Rene-Jean Bensadoun

doi:10.1117/12.425525

26 April 2001 Low-level laser therapy in chemo- and radiation-induced mucositis: results of multicenter phase III studies

Rene-Jean Bensadoun

Author Affiliations +

Proceedings Volume 4422, Low-Level Laser Therapy; (2001) https://doi.org/10.1117/12.425525
Event: Low-Level Laser Therapy, 2001, none, Russian Federation

Abstract

Low of middle energy irradiation with helium-neon laser (LLLT) appears to be a simple atraumatic technique for the prevention and treatment of mucositis of various origins. Preliminary findings obtained by Ciais et al prompted randomized multi-center, double-blind trials to evaluate LLLT for the prevention of a acute chemo- and radiation- induced stomatitis. Irradiation by LLLT corresponds to local application of a high photon density monochromatic light source. Activation of epithelial healing on LLL-treated surfaces, the most commonly recognized effect, has been confirmed by numerous in vitro studies, and is a function of cell type, wavelength, and energy dose. The mechanism of action at a molecular and enzymatic level is currently being studied (detoxification of free-radicals).

Citation Download Citation

Rene-Jean Bensadoun "Low-level laser therapy in chemo- and radiation-induced mucositis: results of multicenter phase III studies", Proc. SPIE 4422, Low-Level Laser Therapy, (26 April 2001); https://doi.org/10.1117/12.425525

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available