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Effects of tissue absorption on statistical properties of biospeckles are studied. The probability density function of intensity and the spatiotemporal cross-correlation function considering light absorption are derived. It is shown theoretically and experimentally that as valves of absorption coefficients increase, the probability density of low light intensity increases and that of high light intensity decreases, which means that dark spots increase and bright spots decrease in bio-speckle pattern. However, the second-order statistics properties of bio-speckles don't' change with the increase of tissue absorption.
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Zhi Zhang, Qingming Luo, Shaoqun Zeng, Xinyu Zhang, Dexiu Huang, "Effect of tissue absorption on statistical properties of biospeckles," Proc. SPIE 4427, Imaging of Tissue Structure and Function, (22 August 2001); https://doi.org/10.1117/12.438412