Fluorescence imaging in the uppper gastrointestinal tract for the detection of dysplasic changes

Uwe Sukowski; Bernd Ebert; Marianne Ortner; Karsten Mueller; W. Voderholzer; J. Weber-Eibel; M. Dietel; Herbert Lochs; Herbert H. Rinneberg

doi:10.1117/12.447130

31 October 2001 Fluorescence imaging in the upper gastrointestinal tract for the detection of dysplasic changes

Uwe Sukowski, Bernd Ebert, Marianne Ortner, Karsten Mueller, W. Voderholzer, J. Weber-Eibel, M. Dietel, Herbert Lochs, Herbert H. Rinneberg

Author Affiliations +

Proceedings Volume 4432, Diagnostic Optical Spectroscopy in Biomedicine; (2001) https://doi.org/10.1117/12.447130
Event: European Conferences on Biomedical Optics, 2001, Munich, Germany

Abstract

During endoscopy of the esophagus fluorescence images were recorded at a delay of 20 ns after pulsed laser excitation simultaneously with conventional reflected white light images. To label malignant cells (dysplasia, tumor) 5-aminolaevulinic acid was applied prior to fluorescence guided bi-opsy. In this way pre-malignant and malignant lesions were detected not seen previously during routine endoscopy.

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Uwe Sukowski, Bernd Ebert, Marianne Ortner, Karsten Mueller, W. Voderholzer, J. Weber-Eibel, M. Dietel, Herbert Lochs, and Herbert H. Rinneberg "Fluorescence imaging in the upper gastrointestinal tract for the detection of dysplasic changes", Proc. SPIE 4432, Diagnostic Optical Spectroscopy in Biomedicine, (31 October 2001); https://doi.org/10.1117/12.447130

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