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31 October 2001 Optical detection of (pre-)malignant lesions of the oral mucosa: autofluorescence characteristics of healthy mucosa
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Abstract
Previous clinical results demonstrate the potential of in vivo autofluorescence spectroscopy for early detection of (pre-)malignant lesions of the oral mucosa. For reliable diagnosis, it is necessary to study autofluorescence spectra of healthy mucosa first. We measured excitation-emission maps in healthy subjects and subjects with a history of cancer in the head -neck region. Our results show that different anatomical locations produce distinct autofluorescence spectra. Influences of, among others, smoking and drinking habits require further investigation.
© (2001) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Diana C. G. de Veld, Max Witjes, Jan L.N. Roodenburg, Willem M. Star, and Hericus J. C. M. Sterenborg "Optical detection of (pre-)malignant lesions of the oral mucosa: autofluorescence characteristics of healthy mucosa", Proc. SPIE 4432, Diagnostic Optical Spectroscopy in Biomedicine, (31 October 2001); https://doi.org/10.1117/12.447135
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