Biomedical applications of coherent-optical methods for the analysis of lymph flow in microvessels

Anastasiya V. Solov'eva; Gregory E. Brill; Ekateryna I. Galanzha; Sergey S. Ulyanov; Valery V. Tuchin; Tatyana V. Stepanova; Alexey V. Sedykh

doi:10.1117/12.446683

24 October 2001 Biomedical applications of coherent-optical methods for the analysis of lymph flow in microvessels

Anastasiya V. Solov'eva, Gregory E. Brill, Ekateryna I. Galanzha, Sergey S. Ulyanov, Valery V. Tuchin, Tatyana V. Stepanova, Alexey V. Sedykh

Author Affiliations +

Proceedings Volume 4434, Hybrid and Novel Imaging and New Optical Instrumentation for Biomedical Applications; (2001) https://doi.org/10.1117/12.446683
Event: European Conferences on Biomedical Optics, 2001, Munich, Germany

Abstract

In the present study the characteristics of lymph microcirculation are investigated. The lymph microcirculation was studied on small intestine mesentery during N^G=nitro=L-arginine (L-NNA) application on intact microvessels and after stress. The direct measurement of lymph flow velocity (parameter V) in individual microvessels was based on the technique of light intravital videomicroscopy. The first spectral moments of Doppler signal characterizing the mean velocities of lymph flow in microvessels (parameters M₁) were measured by the laser- speckle method. Simultaneously, diameters of lymph microvessels as well as parameters of phasic contractions and valve functioning were registered.

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Anastasiya V. Solov'eva, Gregory E. Brill, Ekateryna I. Galanzha, Sergey S. Ulyanov, Valery V. Tuchin, Tatyana V. Stepanova, and Alexey V. Sedykh "Biomedical applications of coherent-optical methods for the analysis of lymph flow in microvessels", Proc. SPIE 4434, Hybrid and Novel Imaging and New Optical Instrumentation for Biomedical Applications, (24 October 2001); https://doi.org/10.1117/12.446683

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