24 October 2001 Modular multiwavelength wideband intensity-modulated optical spectrometer for localized near-infrared spectroscopy
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Abstract
We describe the development of a modular, multiwavelength, wideband intensity-modulated near infrared spectrometer (100MHz -1GHz) capable of simultaneous measurement of three parameters - the dc intensity, the ac intensity and the phase shift of light transmitted through tissue at a high sampling rate. The intended purpose of this instrument is the detection of fast dynamic changes in the reduced scattering coefficient of tissue due to cellular depolarization. The instrument requires sensitivity to small changes in optical pathlength and absorption in small volumes of tissue.
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Iain D. C. Tullis, Mark Cope, David T. Delpy, "Modular multiwavelength wideband intensity-modulated optical spectrometer for localized near-infrared spectroscopy", Proc. SPIE 4434, Hybrid and Novel Imaging and New Optical Instrumentation for Biomedical Applications, (24 October 2001); doi: 10.1117/12.446664; https://doi.org/10.1117/12.446664
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