12 April 2002 Autofluorescence endoscopy for detecting gastrointestinal cancer
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Proceedings Volume 4536, International Workshop on Photonics and Imaging in Biology and Medicine; (2002); doi: 10.1117/12.462524
Event: International Workshop on Photonics and Imaging in Biology and Medicine, 2001, Wuhan, China
Abstract
A cost-effective autofluorescence detecting system has been developed by our research group to diagnose and localize the early gastrointestinal cancer, which is occult to the traditional means of detection, for example, biopsy. At the early stage, we utilize autofluorescence spectrum detected by OMA (Optical Multichannel Analyzer) to discriminate cancerous tissue. Although this method can effectively distinguish tumors from normal tissues, it is not suitable to be applied in clinic use due to the high cost of the- most-often used OMA-autofluorescence detector. Then we designed a novel Double PMTs (Photomultiply Tube) system, which consists of two parallel-working A/Ds with lower frequency of acquisition, to replace the OMA system, and the results of clinic experiments prove that it can effectively determine gastrointestinal cancers.
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Xiaodong Chen, Zhi Xu, Hongbo Xie, Dongqing Chen, Daoyin Yu, "Autofluorescence endoscopy for detecting gastrointestinal cancer", Proc. SPIE 4536, International Workshop on Photonics and Imaging in Biology and Medicine, (12 April 2002); doi: 10.1117/12.462524; http://dx.doi.org/10.1117/12.462524
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KEYWORDS
Cancer

Tissues

Luminescence

Signal detection

Diagnostics

Laser induced fluorescence

Endoscopy

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