28 September 2001 Microfluidic sample preparation for immunoassays
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Proceedings Volume 4560, Microfluidics and BioMEMS; (2001) https://doi.org/10.1117/12.443043
Event: Micromachining and Microfabrication, 2001, San Francisco, CA, United States
Abstract
Researchers at Lawrence Livermore National Laboratory are developing means to collect and identify fluid-based biological pathogens in the forms of proteins, viruses, and bacteria. To support detection instruments, we are developing a flexible fluidic sample preparation unit. The overall goal of this Microfluidic Module is to input a fluid sample, containing background particulates and potentially target compounds, and deliver a processed sample for detection. We are developing techniques for sample purification, mixing, and filtration that would be useful to many applications including immunologic and nucleic acid assays. Many of these fluidic functions are accomplished with acoustic radiation pressure or dielectrophoresis. We are integrating these technologies into packaged systems with pumps and valves to control fluid flow through the fluidic circuit.
© (2001) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Steven R. Visuri, William J. Benett, Kerry Bettencourt, John Chang, Karl A. Fisher, Julia Hamilton, Peter A. Krulevitch, Christina S. Park, Cheryl A. Stockton, Lisa A. Tarte, Amy Wang, Thomas Wilson, "Microfluidic sample preparation for immunoassays", Proc. SPIE 4560, Microfluidics and BioMEMS, (28 September 2001); doi: 10.1117/12.443043; https://doi.org/10.1117/12.443043
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