17 June 2002 Near-infrared welding of aorta and skin tissues using a Cr4+:YAG laser
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Proceedings Volume 4609, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XII; (2002) https://doi.org/10.1117/12.432085
Event: International Symposium on Biomedical Optics, 2002, San Jose, CA, United States
Abstract
We present a study on welding of ex vivo aorta and skin samples using a tunable Cr4+: yttrium aluminum garnet (YAG) laser to explore the wavelength dependence of the welding efficacy. Welding efficacy was monitored by measuring the tensile strength of the welded tissue and the extent of collateral tissue damage. Tensile strengths were measured using a digital force gauge. Full thickness tissue bonding was observed with both aorta and skin samples. The welding of aorta was so perfect that it was difficult to distinguish the welded sites from the non-welded sites on hematoxylin and eosin staining of the samples under optical microscope. No collateral damage of the aorta samples was observed. Scanning Electron Microscopic study of the welded samples supported the optical microscopy results. Best results for aorta and skin were achieved in the 1455-1460 nm range. The weld strength as a function of wavelength correlates with the absorption spectrum of water. Fluorescence imaging of welded aorta and skin shows no significant change in collagen and elastin signal.
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Tapan K. Gayen, Alvin Katz, Yury Budansky, Jonathan M. Evans, Shixiang Xu, Howard E. Savage, Steven A. McCormick, Robert R. Alfano, "Near-infrared welding of aorta and skin tissues using a Cr4+:YAG laser", Proc. SPIE 4609, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XII, (17 June 2002); doi: 10.1117/12.432085; https://doi.org/10.1117/12.432085
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