27 March 2002 Laser biomodulation in bone implants: a Raman spectral study
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Proceedings Volume 4614, Biomedical Vibrational Spectroscopy II; (2002) https://doi.org/10.1117/12.460797
Event: International Symposium on Biomedical Optics, 2002, San Jose, CA, United States
Healing is important for the success of the insertion of implants and for treating traumatic or pathologic injuries of the bone. Lasertherapy has been suggested as a mean of improving bone healing. Raman spectroscopy was used to assess the amount of both inorganic and organic components of irradiated and non-irradiated bone around dental implants inserted in to the tibia. Fourteen rabbits received a titanium implant on the tibia, eight of them were irradiated with 830nm laser and six acted as controls. The animals were sacrificed 15, 30 and 45 days after the surgery, and specimens were prepared for Raman spectroscopy, which was collected at every four points from each three thirds of the bone around the implants. The results showed significant differences in the concentration of inorganic components in irradiated specimens between 15 and 30days, 15 and 45; between irradiated and controls 30 and 45 days after surgery. Concentration of organic components was also significantly different between irradiated and controls in periods of 30 to 45 days after surgery. It is concluded that LLLT does improve bone healing and this can be safely assessed by Raman Spectroscopy.
© (2002) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Cibelle Lopes, Cibelle Lopes, Sokki Sathaiah, Sokki Sathaiah, Antonio Luiz Barbosa Pinheiro, Antonio Luiz Barbosa Pinheiro, Janaina Duarte, Janaina Duarte, Airton Abrahao Martin, Airton Abrahao Martin, Vicente P. P. Cunha, Vicente P. P. Cunha, Marcos T. T. Pacheco, Marcos T. T. Pacheco, "Laser biomodulation in bone implants: a Raman spectral study", Proc. SPIE 4614, Biomedical Vibrational Spectroscopy II, (27 March 2002); doi: 10.1117/12.460797; https://doi.org/10.1117/12.460797

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