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27 March 2002 Near-infrared Raman spectroscopy for detection and classification of gastrointestinal disease
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Proceedings Volume 4614, Biomedical Vibrational Spectroscopy II; (2002) https://doi.org/10.1117/12.460788
Event: International Symposium on Biomedical Optics, 2002, San Jose, CA, United States
Abstract
The prospect of utilising NIR-Raman spectroscopy for analysis of gastro-intestinal (GI) tissue has been explored both with snap-frozen and formalin fixed samples. In the oesophagus large sample numbers have been employed and the full spectrum of pathology has been studied. Multivariate analysis techniques have been employed to optimally separate the groups and spectral diagnostic models have been constructed and evaluated by employing cross-validation testing. Sensitivities have been shown to vary between 73 and 100 percent and specificities between 91 and 100 percent, depending on pathology group and tissue type.
© (2002) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Nicholas Stone, Catherine A. Kendall, Nitya Chandratreya, Neil Shepherd, and Hugh Barr M.D. "Near-infrared Raman spectroscopy for detection and classification of gastrointestinal disease", Proc. SPIE 4614, Biomedical Vibrational Spectroscopy II, (27 March 2002); https://doi.org/10.1117/12.460788
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