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Oxygradient II is an optical spectrometric sensor system for use in the microvolume of tissues (1-2 mm3). The microlightguides used for monitoring have catchment volumes of sizes that enable measurements of critical values at the venous end of capillaries. The Oxygradient II is able to be used for monitoring of all usual optical parameters in most human organs. A non-invasive monitoring during thoracic or abdominal surgery is possible with less-invasive micro-lightguides of diameters of 600 micrometers in combination with thin endoscopes.
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Manfred D. Kessler, Dumitru Iulian Nastac, Peter Koller, "EMPHO-oxygradient II for monitoring in organs during surgery and gastrointestinal diseases," Proc. SPIE 4623, Functional Monitoring and Drug-Tissue Interaction, (5 June 2002); https://doi.org/10.1117/12.469438