Real-time in-situ determination of free Cu(II) at picomolar levels in sea water using a fluorescence lifetime-based fiber optic biosensor

Richard B. Thompson; Hui-Hui Zeng; Carol A. Fierke; Gary Fones; James W. Moffett

doi:10.1117/12.469783

4 June 2002 Real-time in-situ determination of free Cu(II) at picomolar levels in sea water using a fluorescence lifetime-based fiber optic biosensor

Richard B. Thompson, Hui-Hui Zeng, Carol A. Fierke, Gary Fones, James W. Moffett

Author Affiliations +

Proceedings Volume 4625, Clinical Diagnostic Systems: Technologies and Instrumentation; (2002) https://doi.org/10.1117/12.469783
Event: International Symposium on Biomedical Optics, 2002, San Jose, CA, United States

Abstract

A continuing issue in chemical oceanography and environmental monitoring is the need for frequent and continuous monitoring of analytes in complex matrices such as sea water and ground waters. Particularly for analytes at trace levels such as Cu(II) in sea water, sampling and analysis of discrete specimens is costly, slow, labor intensive, employs ship time inefficiently, and risks error by contamination. We have developed a fluorescence lifetime- based fiber optic biosensor which demonstrates real time determination of free Cu(II) in coastal waters, in situ, with a subpicomolar detection limit.

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Richard B. Thompson, Hui-Hui Zeng, Carol A. Fierke, Gary Fones, and James W. Moffett "Real-time in-situ determination of free Cu(II) at picomolar levels in sea water using a fluorescence lifetime-based fiber optic biosensor", Proc. SPIE 4625, Clinical Diagnostic Systems: Technologies and Instrumentation, (4 June 2002); https://doi.org/10.1117/12.469783

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