18 February 2002 Self-organization of protein with helical domains
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Proceedings Volume 4627, Fifth International Workshop on Nondestructive Testing and Computer Simulations in Science and Engineering; (2002) https://doi.org/10.1117/12.456258
Event: Fifth International Workshop on Nondestructive Testing and Computer Simulations in Science and Engineering, 2001, St. Petersburg, Russian Federation
Abstract
In this contribution, we report on a study of the self- organization of isolated polypeptides. The process is computer simulated by the method of molecular dynamics. We observed that the helical structures have a very impotent role in the protein self-organization. We have found conditions under which such structures to be stable. The process and result of self-organization under these conditions were sharply different from others, unable to maintain the helical structures. The structures obtained have a strong resemblance to the native conformations of the corresponding real proteins in a case of proteins composed by helical domains.
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Zakhar M. Frenkel, Alexander I. Melker, "Self-organization of protein with helical domains", Proc. SPIE 4627, Fifth International Workshop on Nondestructive Testing and Computer Simulations in Science and Engineering, (18 February 2002); doi: 10.1117/12.456258; https://doi.org/10.1117/12.456258
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