Color analysis of the human airway wall

Deepa Gopalakrishnan; Geoffrey McLennan M.D.; Martin Donnelley; Angela Delsing; Melissa Suter; Dawn Flaherty; Joseph Zabner; Eric A. Hoffman; Joseph M. Reinhardt

doi:10.1117/12.463600

24 April 2002 Color analysis of the human airway wall

Deepa Gopalakrishnan, Geoffrey McLennan M.D., Martin Donnelley, Angela Delsing, Melissa Suter, Dawn Flaherty, Joseph Zabner, Eric A. Hoffman, Joseph M. Reinhardt

Author Affiliations +

Proceedings Volume 4683, Medical Imaging 2002: Physiology and Function from Multidimensional Images; (2002) https://doi.org/10.1117/12.463600
Event: Medical Imaging 2002, 2002, San Diego, California, United States

Abstract

A bronchoscope can be used to examine the mucosal surface of the airways for abnormalities associated with a variety of lung diseases. The diagnosis of these abnormalities through the process of bronchoscopy is based, in part, on changes in airway wall color. Therefore it is important to characterize the normal color inside the airways. We propose a standardized method to calibrate the bronchoscopic imaging system and to tabulate the normal colors of the airway. Our imaging system consists of a Pentium PC and video frame grabber, coupled with a true color bronchoscope. The calibration procedure uses 24 standard color patches. Images of these color patches at three different distances (1, 1.5, and 2 cm) were acquired using the bronchoscope in a darkened room, to assess repeatability and sensitivity to illumination. The images from the bronchoscope are in a device-dependent Red-Green-Blue (RGB) color space, which was converted to a tri-stimulus image and then into a device-independent color space sRGB image by a fixed polynomial transformation. Images were acquired from five normal human volunteer subjects, two cystic fibrosis (CF) patients and one normal heavy smoker subject. The hue and saturation values of regions within the normal airway were tabulated and these values were compared with the values obtained from regions within the airways of the CF patients and the normal heavy smoker. Repeated measurements of the same region in the airways showed no measurable change in hue or saturation.

Citation Download Citation

Deepa Gopalakrishnan, Geoffrey McLennan M.D., Martin Donnelley, Angela Delsing, Melissa Suter, Dawn Flaherty, Joseph Zabner, Eric A. Hoffman, and Joseph M. Reinhardt "Color analysis of the human airway wall", Proc. SPIE 4683, Medical Imaging 2002: Physiology and Function from Multidimensional Images, (24 April 2002); https://doi.org/10.1117/12.463600

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