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9 May 2002 New approach to elastrograph imaging: modality-independent elastography
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Medicine today relies on palpation as a first line of investigation in the detection and diagnosis of breast cancer. Tissue stiffness (e.g. a lump found in breast tissue) can signal the growth of a potential life threatening cell mass. As such, elastographic imaging techniques (i.e. direct imaging of tissue stiffness) have recently become of great interest to scientists. In this paper, a new method called Modality Independent Elastography (MIE) will be investigated within the context of a mammographic imaging alternative/complement. This new approach uses measures of image similarity in conjunction with computational models to reconstruct images of tissue stiffness. The real strength in MIE is that any imaging modality (e.g. magnetic resonance, computed tomography, ultrasound) in which the image intensity data remains consistent from a pre- to a post-deformed state could be used in this paradigm. Results illustrate: (1) the encoding of stiffness information within the context of a regional image similarity criterion, (2) the methodology for an iterative elastographic imaging framework and (3) successful elasticity reconstructions.
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Michael I. Miga "New approach to elastrograph imaging: modality-independent elastography", Proc. SPIE 4684, Medical Imaging 2002: Image Processing, (9 May 2002);

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