11 April 2002 Image-based retrospective cardiac gating for three-dimensional intravascular ultrasound imaging
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Three-dimensional (3D) intravascular ultrasound provides valuable insight into the tissue characteristics of the coronary wall and plaque composition. However, artifacts due to cardiac motion and vessel wall pulsation limit the accuracy and variability of coronary lumen and plaque volume measurement in 3D IVUS images. ECG-gated image acquisition can overcome these artifacts but results in lengthy acquisition times. Our goal is to reconstruct a 3D IVUS image with negligible vessel pulsation artifacts, by developing an image-based retrospective gating method to track 2D IVUS images belonging to the same cardiac phase. Our approach involves selecting 2D IVUS images belonging to the same cardiac phase from an asynchronously acquired series, by tracking the changing lumen contour over the cardiac cycle. The algorithm was tested using a custom-built coronary phantom and on patient images. 3D non-gated and gated IVUS images were assembled and compared. The extent of pulsation artifacts in the 3D images was estimated by measuring the standard deviation in the shift in the position of the lumen boundary in each cross-sectional slice over the 3D IVUS image. A reduction in pulsation artifact of over 97% was observed in the 3D image assembled using our method.
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Seemantini K. Nadkarni, Seemantini K. Nadkarni, Derek R. Boughner, Derek R. Boughner, Aaron Fenster, Aaron Fenster, } "Image-based retrospective cardiac gating for three-dimensional intravascular ultrasound imaging", Proc. SPIE 4687, Medical Imaging 2002: Ultrasonic Imaging and Signal Processing, (11 April 2002); doi: 10.1117/12.462163; https://doi.org/10.1117/12.462163

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