16 July 2002 Photoacoustic blood glucose and skin measurement based on optical scattering effect
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Non-invasive blood glucose determination has been investigated by more than 100 research groups in the world during the past fifteen years. The commonly optical methods are based on the capacity of near-IR light to penetrate a few hundreds micrometers or a few millimeters into human tissue where it interacts with glucose. A change of glucose concentration may modify the optical parameters in tissue, with the result that its glucose concentration can be extracted by analyzing the received optical signals. This paper demonstrates that glucose affects on the scattering coefficient of human blood, by applying the streak camera and pulsed photoacoustic techniques; and drinking water seems also affecting on PA signal from skin surface.
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Zuomin Zhao, Risto A. Myllyla, "Photoacoustic blood glucose and skin measurement based on optical scattering effect", Proc. SPIE 4707, Saratov Fall Meeting 2001: Optical Technologies in Biophysics and Medicine III, (16 July 2002); doi: 10.1117/12.475582; https://doi.org/10.1117/12.475582

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