15 October 2002 Do infrared light-emitting diodes have a stimulatory effect on wound healing? From an in-vitro trial to patient treatment
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Proceedings Volume 4903, Laser Florence 2001: A Window on the Laser Medicine World; (2002) https://doi.org/10.1117/12.486614
Event: Laser Florence 2001: a Window on the Laser Medicine World, 2001, Florence, Italy
Abstract
Variable effects of different forms of light therapy on wound healing have been reported. This preliminary study covers the efficacy of infrared light emitting diodes (LED) in this domain. Cultured embryonic chicken fibroblasts were treated in a controlled, radomised manner. LED irradiation was performed three consecutive days with a wavelength of 950 nm and a power output of 160 mW, at 0,6 cm distance from the fibroblasts. Each treatment lasted 6 minutes, resulting in a surface energy denstiy of 3,2 J/cm2. The results indicated that LED treatment does not influence fibroblast proliferation at the applied energy density and irradiation frequency (p=0,474). Meanwhile the effects of LED on wound healing in vivo were studied by treating a surgical incision (6 cm) on the lateral side of the right foot in a male patient. The treatment started after 13 days, when initial stitches were being removed. The same parameters as in the in vitro study were used but the treatment was performed five times. The healing could only be evaluated clinically, the irradiated area (2,6 cm) showed a more appropriate contraction, less discoloration and a less hypertrophic scar than the control area (3,4 cm). The used parameters failed to demonstrate any biological effect of LED irradiation in vitro, although the case study on the other hand illustrated a beneficial effect.
© (2002) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Elke Vinck, Elke Vinck, B. Cagnie, B. Cagnie, D. Cambier, D. Cambier, M. Cornelissen, M. Cornelissen, } "Do infrared light-emitting diodes have a stimulatory effect on wound healing? From an in-vitro trial to patient treatment", Proc. SPIE 4903, Laser Florence 2001: A Window on the Laser Medicine World, (15 October 2002); doi: 10.1117/12.486614; https://doi.org/10.1117/12.486614
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