High-sensitivity biosensor based on double metal-cladding waveguide

Guang Chen; Zhuangqi Cao; Xiang Li; Qishun Shen

doi:10.1117/12.481219

28 August 2002 High-sensitivity biosensor based on double metal-cladding waveguide

Guang Chen, Zhuangqi Cao, Xiang Li, Qishun Shen

Proceedings Volume 4904, Optical Fiber and Planar Waveguide Technology II; (2002) https://doi.org/10.1117/12.481219
Event: Asia-Pacific Optical and Wireless Communications 2002, 2002, Shanghai, China

Abstract

A new method of detecting a minute change in refractive index of an analyte is illustrated in this article. Compared with the sensors based on surface plasmon resonance (SPR), we proposed this new structure of sensor based on the theory of guided wave resonance (GWR). In this proposed double metal-cladding waveguide structure, the sample to be probed serves as its guiding layer, and two metal films act as its cladding layer. Both theoretical simulation and experimental results have shown that the sensitivity enhancement factor of GWR over SPR is more than 1 order higher to the magnitude.

Citation Download Citation

Guang Chen, Zhuangqi Cao, Xiang Li, and Qishun Shen "High-sensitivity biosensor based on double metal-cladding waveguide", Proc. SPIE 4904, Optical Fiber and Planar Waveguide Technology II, (28 August 2002); https://doi.org/10.1117/12.481219

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