12 September 2002 [Ca 2+ ]i and MCLA-enhanced ultraweak chemiluminescence of macrophages irradiated with low-intensity He-Ne laser
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Abstract
Low intensity He-Ne laser therapy (eg: intravascular laser irradiation on blood, ILIB) has been wildly used to treat with some illness in clinic but the mechanism remain obscure. Laser power, the irradiation time and the irradiation dose were changed. Laser scanning confocal microscope (LSCM) was used to real-time research the effort of low intensity irradiation on {Ca2+}I in mouse marcophage and single photon counter device (SPC) was used to detect the MCLA enhanced chemiluminescence of macrophage irradiation with low intensity He-Ne laser. Proper dose of low intensity He-Ne laser irradiation can increase the [Ca2+]I of the macrophage and immunocompetence of macrophage effectively. Laser power of 0.16mw is more effect to increase the [Ca2+]i than laser power of 0.40mw. The [Ca2+]i is markedly different even the irradiation dose or the irradiation time is same. Both the irradiation dose and laser power are key factor for the change of [Ca2+]i and immunocopetance of macrophage. Activating ammuno-system of body is one of the very important mechanisms of Low-intensity He-Ne laser therapy.
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Chaoyang Xu, Da Xing, Shici Tan, Xian Li, "[Ca 2+ ]i and MCLA-enhanced ultraweak chemiluminescence of macrophages irradiated with low-intensity He-Ne laser", Proc. SPIE 4916, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment, (12 September 2002); doi: 10.1117/12.483002; https://doi.org/10.1117/12.483002
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