12 September 2002 Construction of tissue autofluorescence spectra by Monte-Carlo simulation
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Abstract
This study investigated a bilayer gastrointestinal normal tissue (including mucosa and submucosa layers) and a cancerous tissue model (including adenoma and submucosa layers), and reconstructed their Laser-Induced Autofluorescence (LIAF) spectra by Monte-Carlo simulation. The good correlation between the reconstructed spectra and experimental spectra suggested that Monte-Carlo simulation can accurately describe the generation and transportation of fluorescence in tissue and therefore can detect cancerous tissue by revealing the real biophysical and biochemical information of tissue.
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Xiaodong Chen, Xiaodong Chen, Hongbo Xie, Hongbo Xie, Zhi Xu, Zhi Xu, Daoyin Yu, Daoyin Yu, } "Construction of tissue autofluorescence spectra by Monte-Carlo simulation", Proc. SPIE 4916, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment, (12 September 2002); doi: 10.1117/12.483003; https://doi.org/10.1117/12.483003
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