Using the Y type fiber, high efficiency fiber coupler and A1GaInP diode laser has developed a new diode laser therapy apparatus with the wavelength of 650nm. The output laser power from the fiber of the apparatus can reach more than 100mW. The fiber localizer of the apparatus is easy for orientation during the therapy and the output laser power is very stable and reliable. The apparatus has been widely used in about 20 hospitals, and has successfully cured more than 50,000 patients who suffered from various diseases, which mainly including cervical spondylosis, traumatic infection, skin bruise, sudden deafness, tympanitis, tinnitus, infantile rhinallergosis, rheumatism, rheumatoism, scapulohumeral periarthritis, asthma, temporomandibular joint disturbance, ulcer, eczema ani, postoperative crissal edema, and so on. The apparatus has also well performed in the application of haematococcus pluvialis's laser mutagenesis breeding.