14 November 2002 Design simulation of DNA-based electronic components
Author Affiliations +
The interest in molecular devices is growing and a number of organic molecules are being studied to achieve commercially viable technology in near future. DNA being the only molecule, which can be, synthesizes in any sequence, orientation and length is a potential candidate for fabrication of Nano devices. It is established fact that life processes are governed by communication through out the length of DNA by charge transfer. Thus, the study of charge transfer in DNA is of great importance in understanding and realisation of DNA based biomolecular electronics. We calculated the ionisation potential of all the four bases of DNA using Harteree Fock Equation with Moller Plesset second harmonic approximation. On the basis of ionisation potential charge transfer in DNA primers has been simulated with respect to sequence and length in light of design of diode, triode and transistors. This paper discusses the calculation of ionisation potentials of individual bases, charge transfer in terms of electron and hole migration. Besides design of electronic components, paper also discusses the application of these calculations in understanding DNA damage chemistry and their experimental validation.
© (2002) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Lalit M. Bharadwaj, Lalit M. Bharadwaj, Inderpreet Kaur, Inderpreet Kaur, Rakesh Kumar, Rakesh Kumar, Ram P. Bajpai, Ram P. Bajpai, } "Design simulation of DNA-based electronic components", Proc. SPIE 4937, Biomedical Applications of Micro- and Nanoengineering, (14 November 2002); doi: 10.1117/12.471948; https://doi.org/10.1117/12.471948

Back to Top