Modeling and processing of laser Doppler reactive hyperaemia signal

Anne Humeau; Jean-Louis Saumet; Jean-Pierre L'Huiller

doi:10.1117/12.516729

1 August 2003 Modeling and processing of laser Doppler reactive hyperaemia signals

Anne Humeau, Jean-Louis Saumet, Jean-Pierre L'Huiller

Proceedings Volume 4948, 25th International Congress on High-Speed Photography and Photonics; (2003) https://doi.org/10.1117/12.516729
Event: 25th international Congress on High-Speed photography and Photonics, 2002, Beaune, France

Abstract

Laser Doppler flowmetry is a non-invasive method used in the medical domain to monitor the microvascular blood cell perfusion through tissue. Most commercial laser Doppler flowmeters use an algorithm calculating the first moment of the power spectral density to give the perfusion value. Many clinical applications measure the perfusion after a vascular provocation such as a vascular occlusion. The response obtained is then called reactive hyperaemia. Target pathologies include diabetes, hypertension and peripheral arterial occlusive diseases. In order to have a deeper knowledge on reactive hyperaemia acquired by the laser Doppler technique, the present work first proposes two models (one analytical and one numerical) of the observed phenomenon. Then, a study on the multiple scattering between photons and red blood cells occurring during reactive hyperaemia is carried out. Finally, a signal processing that improves the diagnosis of peripheral arterial occlusive diseases is presented.

Citation Download Citation

Anne Humeau, Jean-Louis Saumet, and Jean-Pierre L'Huiller "Modeling and processing of laser Doppler reactive hyperaemia signals", Proc. SPIE 4948, 25th International Congress on High-Speed Photography and Photonics, (1 August 2003); https://doi.org/10.1117/12.516729

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available