CO<sub>2</sub> laser soldering of arteriotomy incisions in blood vessels of rats using a temperature-controlled fiber optic system

David Leshem; Tamar Vasilyev; Avi Ravid; Andrea Gat; Naam Kariv; Abraham Katzir; Eyal Gur

doi:10.1117/12.485301

27 June 2003 CO₂ laser soldering of arteriotomy incisions in blood vessels of rats using a temperature-controlled fiber optic system

David Leshem, Tamar Vasilyev, Avi Ravid, Andrea Gat, Naam Kariv, Abraham Katzir, Eyal Gur

Author Affiliations +

Proceedings Volume 4949, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIII; (2003) https://doi.org/10.1117/12.485301
Event: Biomedical Optics, 2003, San Jose, CA, United States

Abstract

Background and objectives: Conventional methods for microvascular anastomosis are normally based on suturing, using special thin nylon sutures. These methods suffer from major drawbacks, which include: anastomosis, which is not watertight, and sutures or clips that cause an inflammatory response. In order to obtain better results, we introduced a procedure based on CO₂ laser soldering. We tested the system on arteriotomy incisions in rat blood vessels, in vivo. Materials and methods: We used a fiber optic based laser soldering system, with a temperature control capability. Arteriotomy incisions of lengths 4±1mm were performed on the femoral arteries of 48 wistar rats: 24 rats in the control group (suture) and 24 rats in the test group (laser soldering). We conducted two follow-up periods: 7 days and 21 days after the surgical procedure, for each group. Flow tests and histology examination were done in order to evaluate the quality of the procedures. Results: The patency rate was 84% for both groups, soldered and sutured. The sutured group showed a significant foreign body reaction (p < 0.05), which was not observed in the soldered group. We found no evidence of thermal damage in the soldered blood vessels. Conclusions: We can conclude that laser soldering is a less traumatic procedure, compared with the conventional suturing technique. It is potentially a faster technique and easier to master.

Citation Download Citation

David Leshem, Tamar Vasilyev, Avi Ravid, Andrea Gat, Naam Kariv, Abraham Katzir, and Eyal Gur "CO₂ laser soldering of arteriotomy incisions in blood vessels of rats using a temperature-controlled fiber optic system", Proc. SPIE 4949, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIII, (27 June 2003); https://doi.org/10.1117/12.485301

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available