Spectroscopic imaging of bladder cancer

Stavros G. Demos; Regina Gandour-Edwards; Rajen Ramsamooj; Ralph de Vere White

doi:10.1117/12.476382

12 September 2003 Spectroscopic imaging of bladder cancer

Stavros G. Demos, Regina Gandour-Edwards, Rajen Ramsamooj, Ralph de Vere White

Proceedings Volume 4949, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIII; (2003) https://doi.org/10.1117/12.476382
Event: Biomedical Optics, 2003, San Jose, CA, United States

Abstract

The feasibility of developing bladder cancer detection methods using intrinsic tissue optical properties is the focus of this investigation. In vitro experiments have been performed using polarized elastic light scattering in combination with tissue autofluorescence in the NIR spectral region under laser excitation in the green and red spectral regions. The experimental results obtained from a set of tissue specimens from 25 patients reveal the presence of optical fingerprint characteristics suitable for cancer detection with high contrast and accuracy. These photonic methods are compatible with existing endoscopic imaging modalities which make them suitable for in-vivo application.

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Stavros G. Demos, Regina Gandour-Edwards, Rajen Ramsamooj, and Ralph de Vere White "Spectroscopic imaging of bladder cancer", Proc. SPIE 4949, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIII, (12 September 2003); https://doi.org/10.1117/12.476382

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KEYWORDS

Cancer

Tumors

Near infrared

Tissue optics

Tissues

Light scattering

Bladder

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