14 July 2003 Qualitative optical-thermal model of argon, selective, and microsecond infrared laser trabeculoplasty
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Proceedings Volume 4951, Ophthalmic Technologies XIII; (2003) https://doi.org/10.1117/12.482372
Event: Biomedical Optics, 2003, San Jose, CA, United States
Abstract
Purpose: The purpose of this work was to develop a model to predict and compare laser-trabecular meshwork interactions during laser trabeculoplasty with three different lasers. Methods: A qualitative multilayer optical-thermal model of the trabecular meshwork was developed. The model was used to estimate the penetration depth and heat diffusion volume during laser trabeculoplasty with a continuous wave argon laser (ALT), a Q-switched frequency-doubled Nd:YAG laser (SLT), and a flashlamp-pumped near-infrared alexandrite or titanium sapphire laser emitting microsecond pulses (μs-IRLT). Results: The model predicts that both SLT and μs-IRLT produce selective heating of pigmented trabecular meshwork cells with negligible heat diffusion to surrounding structures and with a deeper penetration at the IR wavelength. A preliminary quantitative analysis indicates that selective targeting of spherical pigments is achieved as long as the pulse duration remains less than approximately 1μs. Conclusion: The qualitative model indicates that infrared laser trabeculoplasty with microsecond pulses can produce selective targeting of pigemented trabecular meshwork cells with a deeper penetration than SLT.
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Fabrice Manns, Fabrice Manns, Jean-Marie A. Parel, Jean-Marie A. Parel, Viviana Fernandez, Viviana Fernandez, Joseph Stoiber, Joseph Stoiber, Peggy D. Lamar, Peggy D. Lamar, Nelson Salas, Nelson Salas, Francisco Fantes, Francisco Fantes, "Qualitative optical-thermal model of argon, selective, and microsecond infrared laser trabeculoplasty", Proc. SPIE 4951, Ophthalmic Technologies XIII, (14 July 2003); doi: 10.1117/12.482372; https://doi.org/10.1117/12.482372
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