29 July 2003 Application of I&Q detection system in scouting the curative effect of neck squamous cell carcinoma
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Abstract
Near Infrared Spectroscopy (NIRS) has been widely used in cancer imaging spectroscopy because cancer tissue has more blood volume and less oxygen than normal tissue. The neck squamous cell carcinoma is ideal for our study because it’s a surface mass can be easily feel through the skin. We use a simple homodyne phase modulation system, In-phase and Quadrature Phase (I&Q) Detection system, to study the curative effect of therapy in neck cancer patients. Clinical treatment includes mainly chemical and radiation therapy, both of which alter the blood volume and the oxygenation saturation in cancer tissue. The I&Q detection system is capable of the quantification measurement of those biological changes. In this paper, we will simply introduce the I&Q detection system’s principle and constitution, and mainly explain the analysis of patients’ data.
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Jun Zhang, Tao Tu, Ulas Sunar, Xavier Intes, Shoko Nioka, Zhihong Zhang, Alex Kilger, Robert A. Lustig, Laurie A. Loevner, Britton Chance, "Application of I&Q detection system in scouting the curative effect of neck squamous cell carcinoma", Proc. SPIE 4955, Optical Tomography and Spectroscopy of Tissue V, (29 July 2003); doi: 10.1117/12.478177; https://doi.org/10.1117/12.478177
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