29 July 2003 Method to measure the optical properties of small volumes of biological tissues
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Abstract
The method consists in measuring the perturbation provoked by a small volume (0.2-1 ml) of tissue on light propagating through a medium of known optical properties. The absorption and the reduced scattering coefficient of the medium are retrieved from multidistance continuous wave measurements of transmittance. The inversion procedure is based on the solution of the diffusion equation obtained with a perturbative approach. The method has been validated with Monte Carlo results. Experimental results are reported for various kind of tissue. The results obtained shows that the method is particularly effective for low absorbing tissues.
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Fabrizio Martelli, Fabrizio Martelli, Samuele del Bianco, Samuele del Bianco, Giovanni Zaccanti, Giovanni Zaccanti, } "Method to measure the optical properties of small volumes of biological tissues", Proc. SPIE 4955, Optical Tomography and Spectroscopy of Tissue V, (29 July 2003); doi: 10.1117/12.478218; https://doi.org/10.1117/12.478218
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