8 July 2003 Burn depth determination in human skin using polarization-sensitive optical coherence tomography
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Abstract
Accurate evaluation of the depth of injury in burn victims is of considerable practical value to the surgeon, both for initial determination of resuscitation fluid requirements, and in deciding whether excision and closure of the wound is necessary. Currently, burn depth is most accurately evaluated by visual inspection, though decisions concerning treatment may not be possible for a number of days post-injury. As part of our ongoing efforts to provide an objective, quantitative method for burn depth determination, we present here the results of a study using polarization-sensitive optical coherence tomography (PS-OCT) to detect and measure thermally induced changes in collagen birefringence in skin excised from burn patients. We find that PS-OCT is capable of imaging and quantifying significantly reduced birefringence in burned human skin.
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Mark C. Pierce, Mark C. Pierce, Robert L. Sheridan, Robert L. Sheridan, Boris Hyle Park, Boris Hyle Park, Barry Cense, Barry Cense, Johannes F. de Boer, Johannes F. de Boer, } "Burn depth determination in human skin using polarization-sensitive optical coherence tomography", Proc. SPIE 4956, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VII, (8 July 2003); doi: 10.1117/12.478966; https://doi.org/10.1117/12.478966
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