8 July 2003 Dynamic study of irradiated artificial skin using OCT
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Abstract
We report a novel application of optical coherence tomography (OCT), to monitor post-laser irradiation collagen injury in skin model. An artificial skin model (RAFT) which closely approximates human skin, was irradiated with a Perovskite laser (λ = 1341 nm). We investigated dynamic changes in a RAFT after laser irradiation through OCT and compared the results to those of histology. OCT images clearly delineated areas of post-irradiation collagen injury and allowed non-invasive monitoring of the wound healing process. Histology was correlated well with OCT images. OCT has advantages because it is non-invasive and allows serial monitoring at the same site over time. Our study showed that OCT may be a useful tool for determination of optimal parameters for non-ablative laser skin rejuvenation (NALSR) using different devices.
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Woonggyu Jung, Woonggyu Jung, Bunsho Kao, Bunsho Kao, Kristen M. Kelly, Kristen M. Kelly, Zhihua Ding, Zhihua Ding, J. Stuart Nelson, J. Stuart Nelson, Zhongping Chen, Zhongping Chen, } "Dynamic study of irradiated artificial skin using OCT", Proc. SPIE 4956, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VII, (8 July 2003); doi: 10.1117/12.479043; https://doi.org/10.1117/12.479043
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