Multicapillary electrophoresis disposable cartridge for bioseparations

Varoujan David Amirkhanian; Ming-Sun Liu

doi:10.1117/12.478358

18 July 2003 Multicapillary electrophoresis disposable cartridge for bioseparations

Varoujan David Amirkhanian, Ming-Sun Liu

Proceedings Volume 4966, Microarrays and Combinatorial Technologies for Biomedical Applications: Design, Fabrication, and Analysis; (2003) https://doi.org/10.1117/12.478358
Event: Biomedical Optics, 2003, San Jose, CA, United States

Abstract

We have successfully demonstrated the development of a compact and cost-effective parallel multi-channel capillary electrophoresis system for bio-molecules analysis. The automated process includes a buffer/gel replenishment mechanism, high voltage control of fluidics and an automated sample tray transport capability. The bio-separation/analysis occurs in a disposable cartridge containing multi-column capillaries with integrated excitation optical fibers, detection micro-optics and a buffer reservoir common to all separation channels. Tests of this fully integrated system indicate, that large quantities of biological samples can be analyzed automatically in a short period with highly sensitive fluorescence detection.

Citation Download Citation

Varoujan David Amirkhanian and Ming-Sun Liu "Multicapillary electrophoresis disposable cartridge for bioseparations", Proc. SPIE 4966, Microarrays and Combinatorial Technologies for Biomedical Applications: Design, Fabrication, and Analysis, (18 July 2003); https://doi.org/10.1117/12.478358

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