30 May 2003 Graphical user interface for intraoperative neuroimage updating
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Image-guided neurosurgery typically relies on preoperative imaging information that is subject to errors resulting from brain shift and deformation in the OR. A graphical user interface (GUI) has been developed to facilitate the flow of data from OR to image volume in order to provide the neurosurgeon with updated views concurrent with surgery. Upon acquisition of registration data for patient position in the OR (using fiducial markers), the Matlab GUI displays ultrasound image overlays on patient specific, preoperative MR images. Registration matrices are also applied to patient-specific anatomical models used for image updating. After displaying the re-oriented brain model in OR coordinates and digitizing the edge of the craniotomy, gravitational sagging of the brain is simulated using the finite element method. Based on this model, interpolation to the resolution of the preoperative images is performed and re-displayed to the surgeon during the procedure. These steps were completed within reasonable time limits and the interface was relatively easy to use after a brief training period. The techniques described have been developed and used retrospectively prior to this study. Based on the work described here, these steps can now be accomplished in the operating room and provide near real-time feedback to the surgeon.
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Kyle R. Rick, Alex Hartov, David W. Roberts, Karen E. Lunn, Hai Sun, Keith D. Paulsen, "Graphical user interface for intraoperative neuroimage updating", Proc. SPIE 5029, Medical Imaging 2003: Visualization, Image-Guided Procedures, and Display, (30 May 2003); doi: 10.1117/12.479761; https://doi.org/10.1117/12.479761

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