30 May 2003 Using cortical vessels for patient registration during image-guided neurosurgery: a phantom study
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Patient registration, a key step in establishing image guidance, has to be performed in real-time after the patient is anesthetized in the operating room (OR) prior to surgery. We propose to use cortical vessels as landmarks for registering the preoperative images to the operating space. To accomplish this, we have attached a video camera to the optics of the operating microscope and acquired a pair of images by moving the scope. The stereo imaging system is calibrated to obtain both intrinsic and extrinsic camera parameters. During neurosurgery, right after opening of dura, a pair of stereo images is acquired. The 3-D locations of blood vessels are estimated via stereo vision techniques. The same series of vessels are localized in the preoperative image volume. From these 3-D coordinates, the transformation matrix between preoperative images and the operating space is estimated. Using a phantom, we have demonstrated that patient registration from cortical vessels is not only feasible but also more accurate than using conventional scalp-attached fiducials. The Fiducial Registration Error (FRE) has been reduced from 1 mm using implanted fiducials to 0.3 mm using cortical vessels. By replacing implanted fiducials with cortical features, we can automate the registration procedure and reduce invasiveness to the patient.
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Hai Sun, Hai Sun, David W. Roberts, David W. Roberts, Alex Hartov, Alex Hartov, Kyle R. Rick, Kyle R. Rick, Keith D. Paulsen, Keith D. Paulsen, } "Using cortical vessels for patient registration during image-guided neurosurgery: a phantom study", Proc. SPIE 5029, Medical Imaging 2003: Visualization, Image-Guided Procedures, and Display, (30 May 2003); doi: 10.1117/12.479723; https://doi.org/10.1117/12.479723

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