5 June 2003 Distributed image reconstruction for an in-vivo mouse imaging system
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Abstract
Mice have been widely used in various areas of biomedical research such as drug development and genetic engineering. To investigate drug effect or treatment efficacy in the mouse studies, in-vivo mouse imaging modalities have been recently developed. Among various kinds of imaging modalities, micro-CT is expected to be useful in many biological applications since it provides 3-dimensional high-resolution tomographic images. In this study, we have developed a high-resolution micro-CT system using a microfocus x-ray source and a flat panel detector. The flat panel detector contains a CsI scintillator plate, a 2-dimensional photodiode array, and a 12-bit ADC. The photodiode array consists of 2400 x 2400 pixels of 50μm size. In order to improve computing speed in the micro-CT, we have also developed a distributed parallel processing system using multiple computers. The computation-intensive cone-beam reconstruction process has been divided into multiple tasks in a way that each CPU takes care of similar amount of computations. We have linked four desktop computers with dual AMD Athlon processors by Ethernet and optimized the task allocations among them. The developed parallel processing system has shown to have about eight times faster reconstruction speed. It is expected that the distributed image reconstruction technique can be a low cost solution for the in-vivo mouse imaging system.
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Sang Chul Lee, Sang Chul Lee, Jae Yong Han, Jae Yong Han, In Kon Chun, In Kon Chun, Soo Yeol Lee, Soo Yeol Lee, Min Hyoung Cho, Min Hyoung Cho, } "Distributed image reconstruction for an in-vivo mouse imaging system", Proc. SPIE 5030, Medical Imaging 2003: Physics of Medical Imaging, (5 June 2003); doi: 10.1117/12.480006; https://doi.org/10.1117/12.480006
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