5 June 2003 Dynamic susceptometry technique for brain mapping
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Abstract
We have analyzed magnetic field perturbations caused by local magnetic susceptibility changes at a brain when the brain is immersed in the main magnetic field of an MRI system. When a local region of brain tissue is activated, the effective magnetic susceptibility of the region changes due to the blood volume and blood oxygenation level changes at the activated region. This local susceptibility change will, then, perturb the main magnetic field of the MRI system. After estimating the effective magnetic susceptibility change at an activated region, we have analyzed the perturbation field through theoretical and numerical calculations. We have found that the magnetic field perturbation due to the local susceptibility change is as big as can be measured by SQUID devices. We expect that the perturbation field can be used for brain function studies in conjunction with fMRI.
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Soo Yeol Lee, Soo Yeol Lee, Jong Soo Yang, Jong Soo Yang, Sang Chul Lee, Sang Chul Lee, Jae Yong Han, Jae Yong Han, In Kon Chun, In Kon Chun, Min Hyoung Cho, Min Hyoung Cho, } "Dynamic susceptometry technique for brain mapping", Proc. SPIE 5030, Medical Imaging 2003: Physics of Medical Imaging, (5 June 2003); doi: 10.1117/12.480004; https://doi.org/10.1117/12.480004
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