15 May 2003 Fuzzy Region Growing of fMRI Activation Areas
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Conventional analysis of fMRI responses in neuroimaging experiments is typically voxel-wise, i.e. independent of spatial neighbourhood information. However, valid responses are likely to be spatially clustered and connected in 3D space. Identifying spatial relations is commonly considered a pre-processing step, isotropic Gaussian filtering for noise reduction for example. Current post-processing methods consider spatial information but not temporal information; once an activation map is obtained, voxels that do not have a sufficient number of spatial neighbors are simply removed. This paper describes how we have successfully incorporated fuzzy region growing into EvIdent®, an fMRI data analysis application. The method uses spatial-temporal information to enhance spatially connected temporally related activation regions.
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Rodrigo A. Vivanco, Rodrigo A. Vivanco, Nicolino J. Pizzi, Nicolino J. Pizzi, "Fuzzy Region Growing of fMRI Activation Areas", Proc. SPIE 5032, Medical Imaging 2003: Image Processing, (15 May 2003); doi: 10.1117/12.480176; https://doi.org/10.1117/12.480176

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