15 May 2003 High-resolution reconstruction for 3D SPECT
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In this work, we have developed a new method for SPECT (single photon emission computed tomography) image reconstruction, which has shown the potential to provide higher resolution results than any other conventional methods using the same projection data. Unlike the conventional FBP- (filtered backprojection) and EM- (expectation maximization) type algorithms, we utilize as much system response information as we can during the reconstruction process. This information can be pre-measured during the calibration process and stored in the computer. By selecting different sampling schemes for the point response measurement, different system kernel matrices are obtained. Reconstruction utilizing these kernels generates a set of reconstructed images of the same source. Based on these reconstructed images and their corresponding sampling schemes, we are able to achieve a high resolution final image that best represents the object. Because a uniform attenuation, resolution variation and some other effects are included during the formation of the system kernel matrices, the reconstruction from the acquired projection data also compensates for all these effects correctly.
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Tianfang Li, Tianfang Li, Junhai Wen, Junhai Wen, Hongbing Lu, Hongbing Lu, Xiang Li, Xiang Li, Zhengrong Liang, Zhengrong Liang, "High-resolution reconstruction for 3D SPECT", Proc. SPIE 5032, Medical Imaging 2003: Image Processing, (15 May 2003); doi: 10.1117/12.481429; https://doi.org/10.1117/12.481429

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