A fiber-optic-based biosensor to monitor mutans streptococci in saliva

Anil Kishen; M. S. John; Chu Sing Lim; Anand Asundi

doi:10.1117/12.518766

13 October 2003 A fiber-optic-based biosensor to monitor mutans streptococci in saliva

Anil Kishen, M. S. John, Chu Sing Lim, Anand Asundi

Author Affiliations +

Proceedings Volume 5068, Saratov Fall Meeting 2002: Optical Technologies in Biophysics and Medicine IV; (2003) https://doi.org/10.1117/12.518766
Event: Saratov Fall Meeting 2002 Laser Physics and Photonics, Spectroscopy, and Molecular Modeling III; Coherent Optics of Ordered and Random Media III, 2002, Saratov, Russian Federation

Abstract

A fiber optic biosensor to monitor mutans streptococci activity in human saliva is discussed. The developed biosensor is based on the selective bacterial growth medium and evanescent wave spectroscopy at the core-cladding interface of a multimode fiber to monitor the bacterial mediated biochemical reaction. In order to achieve this, a short length of the cladding is removed; the fiber core surface is treated and coated with a thin film of porous glass medium using sol-gel technique. During experiments, the mutans streptococci mediated reaction with sucrose is monitored using a photosensitive indicator, which is immobilized within the porous glass coating. This investigation highlights the potential benefits of the FOBS to monitor mutans streptococci activity in saliva.

Citation Download Citation

Anil Kishen, M. S. John, Chu Sing Lim, and Anand Asundi "A fiber-optic-based biosensor to monitor mutans streptococci in saliva", Proc. SPIE 5068, Saratov Fall Meeting 2002: Optical Technologies in Biophysics and Medicine IV, (13 October 2003); https://doi.org/10.1117/12.518766

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