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21 August 2003 Laser microradar technique for eye fundus investigation
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Current treatments for vascular disorders in retina include laser surgery and laser therapy to eliminate the crucial influence of abnormal blood vessels. Three alternatives are in use: laser photocoagulation surgery, photodynamic therapy, and transpupillary laser thermotherapy. Even sophisticated laser-based devices and arrangements, in practice today, do not solve the problem of adequate dosage of the irradiation, that is an extremely critical matter. As an indirect source of information about the temperature and irradiation dosage, the changes of relief during tissue heating are proposed to be used. Temperature difference between treated and untreated zones achieves 10°C and more. The growth of temperature of the irradiated tissue leads to dimension changes, and thus to the changes of the topography of eye bottom. We studied a known phase difference double-beam interferometric technique modified in such a way, that a reference beam is kept in a reference position without scanning. A second, frequency-shifted beam is scanned along a trajectory crossing treated and untreated zones of the eye bottom. Changes in phase structure are analyzed to have a judgment on thermal processes in retina. Experimentally, eye model was used with a retina movable by means of a micro-screw. Sensitivity of the order of 0.1 μm was got. We recommend further studies on a live tissue, affected by laser radiation.
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Vasyl Molebny "Laser microradar technique for eye fundus investigation", Proc. SPIE 5086, Laser Radar Technology and Applications VIII, (21 August 2003);

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