Smart drug delivery system based on pyrotechnical actuation

Manel Puig-Vidal; Jaime Lopez; Pere Miribel; Josep Samitier-Marti; Carole Rossi; Axel Berthold

doi:10.1117/12.501509

18 April 2003 Smart drug delivery injector microsystem based on pyrotechnical actuation

Manel Puig-Vidal, Jaime Lopez, Pere Miribel, Josep Samitier-Marti, Carole Rossi, Axel Berthold

Proceedings Volume 5119, Bioengineered and Bioinspired Systems; (2003) https://doi.org/10.1117/12.501509
Event: Microtechnologies for the New Millennium 2003, 2003, Maspalomas, Gran Canaria, Canary Islands, Spain

Abstract

A smart drug delivery injector microsystem is presented based on small pyrotechnics to impulse drugs to be injected to a human being. The proposal refers to a feasibility demonstration of the technology for pharmaceutical chips. These chips would be around some cm2 in section and will be able to inject a drug into de subject skin responding to an electrical signal. The product derived from this activity will be useful for astronaut's health, being able to administrate emergency doses of products (for instance cardio-tonic or hypoallegic drugs) enough to survive an emergency situation (as it can be a heart attack during EVA). The system can also be used for easy administration of drugs needed for physiological research. The usefulness of the device in terrestrial applications has no doubt, allowing remote administration of drugs to patients whose biomedical parameters are remotely monitored. The concept proposed here is new in combining the idea of pharmaceutical chip with the ultrasonic droplet technology and the use of pyrotechnics to provide energy to the drug to be injected. The proposed Drug Injector Microsystem is based on 2 main blocks:- Micropyrotechnic system: defines the ignition part based on pyrotechnic.- Microfluidic system: defines the drug injection part. This part is also divided in different critical parts: Expansion chamber, membrane or piston, drug reservoir and a needle. Different sensors are placed on the expansion chamber of microfluidic system and on the micropyrotechnic system. A complete electronic module is implemented with a PC interface to define flexible and user friendly experiences showing the smart drug delivery injector microsystem principle.

Citation Download Citation

Manel Puig-Vidal, Jaime Lopez, Pere Miribel, Josep Samitier-Marti, Carole Rossi, and Axel Berthold "Smart drug delivery injector microsystem based on pyrotechnical actuation", Proc. SPIE 5119, Bioengineered and Bioinspired Systems, (18 April 2003); https://doi.org/10.1117/12.501509

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