2 October 2003 Optical coherence tomography in clinical examinations of nonpigmented skin malignancies
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Optical coherence tomography (OCT) images of basal cell carcinomas (BCCs) have been acquired using a compact handheld proble with an integrated video camera allowing the OCT images to be correlated to a skin surface image. In general the healthy tissue of the skin has an obvious stratified structure, whereas the cancerous tissue shows a more homogeneous structure. Thus it was demonstrated that it is possible to distinguish BCCs from healthy tissue by means of OCT. Furthermore different histological types of BCC were identified. Comparison of OCT images taken prior to and immediately after photodynamic theory clearly shows the tissue response to the treatment, and indicates local oedema in the treated area.
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Laura K. Jensen, Laura K. Jensen, Lars Thrane, Lars Thrane, Peter E. Andersen, Peter E. Andersen, Andreas Tycho, Andreas Tycho, Finn Pedersen, Finn Pedersen, Stefan Andersson-Engels, Stefan Andersson-Engels, Niels Bendsoe, Niels Bendsoe, Sune Svanberg, Sune Svanberg, Katarina Svanberg, Katarina Svanberg, } "Optical coherence tomography in clinical examinations of nonpigmented skin malignancies", Proc. SPIE 5140, Optical Coherence Tomography and Coherence Techniques, (2 October 2003); doi: 10.1117/12.500665; https://doi.org/10.1117/12.500665

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