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8 October 2003 Raman spectroscopy in the assessment of breast cancer and axillary lymph node metastases
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Abstract
Raman Spectroscopy is an optical diagnostic technique applied in this study to characterise breast tissue by biochemical signature spectra. In cross-validated results, Raman Spectroscopy identifies invasive breast carcinoma with 75 - 97% agreement with Histology opinion. Axillary lymph nodes from patients with breast carcinoma were mapped with confocal Raman Spectroscopy and colour-weighted principal component analysis (PCA) images were used to identify local biochemical features and correlate these with parallel section slides analysed with routine histology.
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Jenny Smith, Catherine Kendall, Jay Christie-Brown, Alastair Sammon, and Nicholas Stone "Raman spectroscopy in the assessment of breast cancer and axillary lymph node metastases", Proc. SPIE 5141, Diagnostic Optical Spectroscopy in Biomedicine II, (8 October 2003); https://doi.org/10.1117/12.500472
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