16 October 2003 Thermal effects in IR-laser-irradiated living cells
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Irradiation of cell-layers with focussed 2.8 μm ir-laser allows to control the cell temperature from room temperature up to 100°C. Temperatures were calculated for a cell culture model and verified experimentally by thermal mapping of the cell-surrounding medium by means of thermochromic liquid crystals (TLC). Irradiation power and time were varied and associated biological effects like necrosis and apoptosis were observed with respect to the irradiation dosis.
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Thomas H. Meier, Thomas H. Meier, Angelika C. Rueck, Angelika C. Rueck, Claudia Scalfi-Happ, Claudia Scalfi-Happ, Hubert Hug, Hubert Hug, Marion E. Schneider, Marion E. Schneider, } "Thermal effects in IR-laser-irradiated living cells", Proc. SPIE 5142, Therapeutic Laser Applications and Laser-Tissue Interactions, (16 October 2003); doi: 10.1117/12.501158; https://doi.org/10.1117/12.501158

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