14 October 2003 New method for confocal microscopy and its endoscopic application
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Today, confocal microscopy is widely used in biomedical applications, since its technology allows e.g. in cell biology to resolve sub- and intercelluar details in three-dimensions. Moreover, the recent miniaturization process of opto-electronical components even indicates a possible endoscopic application - to intraoperative examinations without need for a surgical biopsy. The current development of such a confocal endomicroscope, based on the concept of miniaturized fiberoptical components is described. The technical setup is explained in the context of an alternative method for confocal microscopy employing a Digital Micromirror Device (DMD). Moreover, in-vivo tissue staining techniques suitable for confocal endoscopic imaging are analyzed.
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Ingo Krohne, Ingo Krohne, Tilo Pfeifer, Tilo Pfeifer, Frank Bitte, Frank Bitte, Michael Zacher, Michael Zacher, Richard Meier, Richard Meier, } "New method for confocal microscopy and its endoscopic application", Proc. SPIE 5143, Novel Optical Instrumentation for Biomedical Applications, (14 October 2003); doi: 10.1117/12.500763; https://doi.org/10.1117/12.500763


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