CONFERENCE PROCEEDINGS
Advanced Search >
Home > Proceedings > Volume 5221 > Article
Translator Disclaimer
28 October 2003 An electrochemical surface-enhanced Raman spectroscopy approach to anthrax detection
Xiaoyu Zhang; Chanda Ranjit Yonzon; Richard P. Van Duyne
Author Affiliations +
Proceedings Volume 5221, Plasmonics: Metallic Nanostructures and Their Optical Properties; (2003) https://doi.org/10.1117/12.508519
Event: Optical Science and Technology, SPIE's 48th Annual Meeting, 2003, San Diego, California, United States
Abstract
Metal film over nanosphere (MFON) electrodes are excellent substrates for surface-enhanced Raman scattering (SERS) spectroscopy. These surfaces are produced by vapor deposition of a metal film over nanospheres that are assembled in a hexagonally close packed arrangement. The efficiency and reproducibility of AgFON electrode as SERS substrates are confirmed by the repeatability of the electrochemical surface enhanced Raman scattering spectra of pyridine and the Ru(bpy)33+/Ru(bpy)32+ complexes adsorbed on AgFON electrodes. The Raman signal for AgFON electrodes is observed to be extremely stable even at extremely negative potentials in both aqueous and nonaqueous electrolytes. Recent reports have indicated that SERS enhancement factors of up to 14 orders of magnitude can be achieved, providing the sensitivity requisite for ultra trace level detection of target analytes. For this reason, we are developing a method for bacterial endospore SERS detection based on the endospores marker -- dipicolinic acid (DPA). The SERS spectra of dipicolinic acid in aqueous solutions are reported. The dipicolinate vibrational features could be observed in the SERS spectra at the concentration as low as 8 × 10-5 M in 5 minutes. These limits of detection are entirely controlled by the thermodynamics and kinetics of DPA binding to the AgFON surface.
© (2003) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Xiaoyu Zhang, Chanda Ranjit Yonzon, and Richard P. Van Duyne "An electrochemical surface-enhanced Raman spectroscopy approach to anthrax detection", Proc. SPIE 5221, Plasmonics: Metallic Nanostructures and Their Optical Properties, (28 October 2003); doi: 10.1117/12.508519; https://doi.org/10.1117/12.508519
ACCESS THE FULL ARTICLE
PERSONAL SIGN IN
Full access may be available with your subscription
 
Forgot your username?
Forgot your password?
No SPIE account? Create an account
or Institutional Sign In via Shibboleth
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $14.40
Non-members: $18.00 ADD TO CART
PROCEEDINGS
 10 PAGES
DOWNLOAD PDF SAVE TO MY LIBRARY
SHARE
GET CITATION
< Previous Article
|
Next Article >
Advertisement
Advertisement
KEYWORDS
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top