15 December 2003 Lab-on-a-chip optical detection system using plastic fiber optics
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Proceedings Volume 5260, Applications of Photonic Technology 6; (2003) https://doi.org/10.1117/12.543333
Event: Applications of Photonic Technology, 2003, Quebec City, Québec, Canada
Abstract
A new optical detection system for microfluidic lab-on-a-chip applications is described. The photomultiplier tube (PMT) system is controlled by LabVIEW and has output/primary current gains that are programmable from 104 to 107. Light is delivered to and from microfluidic systems by a custom launch-and-detect fiber probe fabricated from one-millimeter plastic optical fibers. The noise characteristics are descrbied and the detection of fluorescent 15μm polystyrene spheres is demonstrated. Using the measured static spatial response of the tip, the velocities of moving microparticles can be calculated from dynamic measurements of their fluorescence.
© (2003) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
James N. McMullin, H. Qiao, Sanket Goel, S. A. McColman, A. Grundmann, "Lab-on-a-chip optical detection system using plastic fiber optics", Proc. SPIE 5260, Applications of Photonic Technology 6, (15 December 2003); doi: 10.1117/12.543333; https://doi.org/10.1117/12.543333
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