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15 March 2004 Benzene degradation pathways investigated by a human-tissue-based biosensor
Luigi Campanella, Patrizia Ercole, Rosella Grossi, Mario Vincenzo Russo, Giovanni Visco
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Proceedings Volume 5261, Smart Medical and Biomedical Sensor Technology; (2004) https://doi.org/10.1117/12.515600
Event: Optical Technologies for Industrial, Environmental, and Biological Sensing, 2003, Providence, RI, United States
Abstract
Benzene is determined by a biosensor based on human kidney tissue as biological component. Dioxygenase catalyse substrate oxidation. The useful analytical range results to be complementary to that of one or more traditional models based on Pseudomonas. The biosensors has got an other aim as its functioning is able to clear up the degradation pathways of benzene. The behavior of a biosensor based on cancerous human kidney tissue compared to healthy one let to hypothize a poor activity of dioxygenase in cancerous kidney, possibly to be tested with prevention strategy.
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Luigi Campanella, Patrizia Ercole, Rosella Grossi, Mario Vincenzo Russo, and Giovanni Visco "Benzene degradation pathways investigated by a human-tissue-based biosensor", Proc. SPIE 5261, Smart Medical and Biomedical Sensor Technology, (15 March 2004); https://doi.org/10.1117/12.515600
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KEYWORDS
Biosensors
Kidney
Tissues
Biological research
Oxidation
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