15 March 2004 Study of the design of micromixer and inspection of mixing efficiency
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Proceedings Volume 5261, Smart Medical and Biomedical Sensor Technology; (2004) https://doi.org/10.1117/12.515191
Event: Optical Technologies for Industrial, Environmental, and Biological Sensing, 2003, Providence, RI, United States
Rapid mixing is essential in many of the micro-fluidic systems targeted for use in the testing of biochip analysis, drug delivery, and analysis or synthesis of blood, among others. A design of a passive micro-mixer is presented in this paper. The mixing is based on the vortex phenomenon of fluid stirring and diffusion. The size of the mixer chip is 10mm×10mm, with a width of the channel of 200μm and a depth of 50μm. This mixer allows fast mixing of small amounts of liquids. A mathematical model that uses gray level contrast to evaluate the mixing efficiency is also proposed. The measurement principle is based on the statistical concept via a quadratic weighting distribution. Experimental results show that the mixing efficiency is over 80% for mixing two liquids with the same polarization and roughly 90% for the mixing of two inks. Thus a new type of biochip can be easily implemented with this system for the application in biomedical diagnostic technology.
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Ya-Hui Hu, Ya-Hui Hu, Ming Chang, Ming Chang, } "Study of the design of micromixer and inspection of mixing efficiency", Proc. SPIE 5261, Smart Medical and Biomedical Sensor Technology, (15 March 2004); doi: 10.1117/12.515191; https://doi.org/10.1117/12.515191

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